
“Development of nanotheranostic for antimicrobial susceptibility testing of diabetic foot infections at the Nelson Mandela Bay Metro.”
Country of Study
South Africa
Institution
Nelson Mandela University
Expected Year of Completion
2027
Thematic Area
Health and Life Sciences
Education
Vuyiseka holds a Master’s degree in Pharmacy from Nelson Mandela University in South Africa. She is currently pursuing a PhD in General Health Science at the same institution, where she has successfully defended her research proposal. Vuyiseka has completed her coursework requirements for her PhD and is expected to graduate in December 2027. She works as a Lecturer at Nelson Mandela University.
Research Summary
Vuyiseka’s research focuses on the growing challenge of managing Diabetic Foot Ulcers (DFUs), a severe complication of diabetes mellitus linked to high morbidity and mortality. With the increasing prevalence of DFUs and antimicrobial resistance (AMR), current treatments are proving ineffective, primarily due to the lack of specific diagnostic tools. This study aims to investigate the microbial profile of infections in DFUs in the Nelson Mandela Bay Metro, identifying resistance patterns and developing a theranostic nanosystem for rapid detection and antimicrobial susceptibility testing (AST). The goal is to improve diagnostic accuracy, enable more effective and timely treatments, and reduce healthcare costs by offering a Point of Care (POC) solution. By addressing the gap in diagnostic capabilities, this research aims to enhance treatment outcomes, reduce amputation rates, and contribute to global efforts to combat AMR.
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