“New typhoid drug development through anti-salmonella potentials of Syzygium guineense Var guineense: An In silico and in vitro and in vivo bio-guided exploratory approach.”
Country of Study
Cameroon
Institution
The University of Bamenda
Expected Year of Completion
2026
Thematic Area
Health and Life Sciences
Education
Tashie holds a Master’s degree in Biochemistry with a minor in Pharmacology and Toxicology from The University of Bamenda in Cameroon. She is currently pursuing a PhD in Biochemistry with a focus on Phytopharmacology at the same university. Tashie has completed her coursework and successfully defended her research proposal. She is expected to complete her PhD in December 2026.
Research Summary
Tashie’s research tackles the growing issue of Salmonella infections in developing countries, particularly in Cameroon, where high typhoid fever rates and rising antibiotic resistance complicate treatment. Traditional antibiotics are becoming less effective due to multidrug resistance, highlighting the need for alternative therapies. This study investigates Syzygium guineense, a medicinal plant used traditionally to treat infections, as a potential anti-Salmonella agent. By combining traditional knowledge with modern pharmacological techniques such as phytochemical profiling, molecular docking, and in vitro testing, the research aims to validate the antibacterial and antioxidant properties of S. guineense. This dual-target approach could provide an affordable, natural alternative to combat antibiotic-resistant infections, contributing to sustainable health solutions in high-burden regions.
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