“Evaluation of immunomodulatory properties of short-chain fatty acids produced by the gut microbiome on immune cell functions in TB patients”
Country of Study
South Africa
Institution
Stellenbosch University
Expected Year of Completion
2026
Thematic Area
Health and Life Sciences
Education
Loide Shipingana holds a Master of Science degree in Molecular Biology from JSS Academy of Higher Education and Research in India. She is currently pursuing a PhD in Molecular Biology at Stellenbosch University in South Africa, with completion expected in 2026.
Research Summary
Loide’s research explores the role of the microbiome and metabolites in tuberculosis (TB) pathogenesis. While microbiome metabolites are known to influence immune responses, their impact on individuals with active TB and post Tb treatment remains under-explored. The study compares different sample types and disease states to identify immunological profiles linked to microbiome abundance and diversity. In vivo experiments will explore how microbiome metabolites affect immune cells’ ability to control Mycobacterium tuberculosis (M.tb) growth. The research aims to identify potential biomarkers for TB progression and post-TB lung disease.
Publications:
