“An Integrated Multi-omics Approach to Understanding Schistosomiasis Associated Bladder Pathology and Tumorigenesis”
Country of Study
Nigeria
Institution
University of Ibadan
Expected Year of Completion
2027
Thematic Area
Life and Health Sciences
Education
Adedoyin Adeboye is pursuing her PhD in Zoology at the University of Ibadan in Nigeria, and works as a Molecular Scientist at Katchey Laboratories Limited. She has an MSc in Cell Biology and Genetics also from the University of Ibadan, and is expecting to complete her studies in 2027.
Research Summary
In Nigeria, poor and late diagnosis of urothelial bladder cancer prevents early intervention. This is because available diagnostic tools are sophisticated and mostly invasive, necessitating visits to modern healthcare facilities with technical experts. These healthcare facilities are, however, inaccessible to primary endemic remote rural communities. This need has inspired questions regarding mechanisms by which the UGS causative parasite, S.haematobium contributes to the development of bladder cancer. While early infection can be quickly remedied, mature Schistosomiasis Associated Bladder Pathology (SABC) is mostly irremediable. Investigating the molecular determinants of UGS progression and early SABC tumorigenesis (prior to malignancy) is important in developing early non-invasive diagnostic tools for the disease and reducing morbidity in UGS endemic settings globally.
Publications:
1. Variation in Arsenic Metabolism in Schistosomiasis Associated Bladder Pathology in a Rural Community, Eggua, Ogun State, Nigeria
